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Stem Cells

Stem Cell Therapy Administration Techniques

Adminstrations techniques used in our stem cell therapy treatments:


Here are the available administration techniques that are used in our stem cell therapy protocoIs. Different types of patient condition will use different forms of injection routes. These are done to give the stem cells into the area that will produce the most positive results for that condition.
 

Intravenous injection

 
Given by injection or infusion into a vein via a small cannula.
 

Lumbar puncture injection

 
Placing cells into the cerebro-spinal fluid, which circulates through the brain and spinal cord. The patient lies down on his or her left side and the doctor prepares the skin for the injection with a disinfectant as for surgery. A very fine needle, too small to feel, is used to anaesthetise the skin over the 3rd to 4th lumbar vertebrae. After this a longer needle is used to anaesthetise the injection track. A spinal needle is then inserted along this track into the subdural space and, once CSF is aspirated, the cells are injected, followed by a small amount of saline to make sure all the cells are in.
 
Sometimes patients develop a headache and are therefore all kept in the clinic for the day and then sent back in the evening with a nurse to accompany them. Analgesia is provided always.
 

Subconjunctival injection

 
Subconjunctival injections offer a steady delivery of cells to the eye, but not in the way that you may think. While the eye will absorb some of the cells directly from a subconjunctival depot, most of the cells will move from the conjunctiva to the tear film. These cells are delivered by the tear film and absorbed through the cornea into the vitreous chamber of the eye.

The Injection will be performed with the patient seated or in the semi-prone position. The application of two drops of topical anesthetic to both eyes to control blinking and decrease sensation to conjunctival manipulation. In almost all cases, subconjunctival injections are made to either the supra- or infratemporal region of the eye. This avoids extraocular muscle insertions. And, with the patient's gaze directed nasally, it offers a relatively large target area.
Once the eye is anesthetized, your doctor will direct the patient's gaze away from the injection, using toothed forceps to gently pinch the conjunctiva at the injection site and lift it from the surface of the globe.

This results in a "tenting" of the conjunctiva off the globe. Only 1-3mm of the needle pierces the conjunctiva, and the actual stab is made well off the surface of the globe. (This manoeuvre greatly reduces the risk of globe perforation.) With the needle placed tangential to the globe, they will pass the needle tip into this tent, and deliver the cells. After the medication is injected, they will remove the needle and release the conjunctival tent.

 


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