Treatment of ALS Is Now Possible With Stem Cells: Amyotrophic Lateral Sclerosis is a rare neurological disorder which is mainly related to nerves cells. Our neurons are responsible for the muscle movements, like chewing, talking, breathing,etc. It is a severity disease which means it will be increasing over the course of time. The word Amyotrophic is a geek word where “A” is no, “myo” stands for muscles and “trophic” which means nourishment. Till now there was no cure for this disease, but stem cells are being its new ray of hope.
We all know that neurons act as messengers in our body; they receive the message from the brain and transmit it to the spinal cord and the muscles throughout the body. However, when these neurons start dying or degenerating, then that stage is considered to be Amyotrophic Lateral Sclerosis (ALS) syndrome. The early signs of this disease are that the muscles get stiff or weak, and then gradually all voluntary muscles get affected. Moreover, the person faces difficulties in breathing, speaking, eating,etc.
Mostly the symptoms of ALS are overlooked but as the time passes they become more severe and may even turn to atrophy. The early symptoms can be muscle twitches in arms, legs or tongue, muscle cramps, difficulty in chewing or swallowing, stiff and tight muscles. Many people who are affected by ALS have observed that the first sign has been seen in arm or hands; they are unable to do regular chores such as writing, opening a lock with the key, or putting the buttons of their shirts, hence one cannot say precisely that from where they got the first sign or symptom.
The causes of ALS are not known, but a study in 1993 showed that the patient’s body produced Cu/Zn superoxide dismutase (SOD1) which was associated with some cases of ALS. The primary cause can be considered as genetics, many scientists in the there study have found out that the mutant SOD1 can become toxic. Even the environmental factors such as diet, infection agents, and viruses can also be the causes. There are no single tests that can detect ALS. The physician has to review the medical history and then conduct neurologic examinations time to time to check whether the symptoms are getting worse or not. The primary diagnosis is made by observing the signs and symptoms by the physician only after that the series of tests begins. These tests can be electromyography (EMG) wherein the electrical ability of the muscle fibers is checked through special recordings. Then there is Nerves Conduction Study (NCS) this test is done on the nerves. The doctor may also refer Magnetic Resonance Test (MRI) including a set of laboratory tests such as urine and blood tests.
As stated earlier there has been no sure shot cure has been found out for this ALS disease but certainly, the researches have been going on since ages. Moreover, through this, there is the biggest development in the form of stem cells.
Stem cells are the set of undifferentiated biological cells that can be changed into specialized cells they can even be divided to get more stem cells. The sources for these stem cells are embryos that are formed during blastocyst phase and secondly the adult tissues. These adult cells can be found throughout the human body, and they have the ability to multiply and grow on their own, but they grow only when there is a tissue injury, or they are activated by any disease otherwise they remain in a non-divisible state throughout their lives. These cells are majorly found in the brain, blood, blood vessels, skin, and bone marrow. The blastocyst and embryos are when the human is developing inside the womb. These days’ people have started preserving the umbilical cords of their new born babies. The reason behind this storage is that this cord consists of a large number of stem cells which can be beneficial for any future mishaps. However, this cord is only accepted for preservation when the tests such as HIV I&II, CMV,HCV,IgG/IgM, syphilis IgG/IgM antibodies and Hepatitis B surface antigen hold negative and even it should be free from fungal and bacterial contamination. The modern medical science sees a lot is potential in stem cells. As they say that there are no limits of diseases that can be cured through stem cells to name a few there are cancers, diabetes, Parkinson’s, Alzheimer’s and much more. Moreover, this list now contains ALS. Yes, this has been exciting news and patients have got new hope to get cured.
So basically it is an ALS stem cell therapy, in this, the most attractive and multipotent cells that are Mesenchymal Stem Cells (MSCs) are used, due to their plasticity and the ability to provide growth factors which modulate the immune system.
The transplantation of Mesenchymal Stem Cells (MSCs) leads to the increase in the survival of neurons as these cells are known to produce proteins that are helpful in the growth and survival of developing as well as mature neurons. Moreover, the idea of replacing the dying neurons with new stems cells has been more realistic, feasible and appealing. The patients who have been treated with stem cells have shown improvements in coordination, balance, speech, swallowing and few other areas as well.
Now the important thing to remember that ,every patient is different and also reacts differently to the medical treatments. As age is one of the biggest factors, the more we grow, the less our body becomes responsive towards the treatments. The persons who got them treated with stemcells21 have shown progressive results within months after their treatments.
The supportive therapies included in our ALS programs are:
• The stem cell repair mode stimulators: the rejuvenation peptide injections
• Self-administration enzyme therapy for 30 days
• Customized nutrition packages based on your blood tests
• Tissue laser therapy
• Oxygen therapy