Is there a way to slow down the aging process and lessen its effects on our bodies?
According to new research findings, the key to achieving such objectives can be found in the wrinkles located inside our cells as opposed to those that line our faces. This means that if scientists could discover a way to fix such wrinkles, then they could possibly reverse the aging process in its entirety.
In some cases, people may experience symptoms of aging earlier than expected because of illnesses such as fatty liver disease, diabetes, cancer, cardiovascular disease, or underlying health conditions such as Alzheimer’s. Furthermore, some researchers still believe that even in the face of all these mitigating factors, analyzing the effects of aging at the cellular level will provide us with the knowledge needed to reverse the aging process.
Researchers working at the University Of Virginia School Of Medicine situated in Charlottesville, discovered that the nuclei found within our cells typically wrinkle as we get older, which means that they can also affect the body in multiple other ways.
What are cellular wrinkles and their correlation to various health issues?
According to stem cell researchers, the position of our DNA inside the nucleus is of great importance. This is because when DNA genes are turned off, they get pushed up against the membrane which covers the nucleus. As a result, this membrane starts to become wrinkly and bumpy, which in turn prevents the genes from switching off as they ought to.
For instance, fatty liver disease is a condition that is usually associated with aging. This is because it is during this process that the nuclear membrane stops functioning properly and ends up releasing the DNA that is supposed to be turned off. This kind of situation is what turns your liver cell into a little fat cell.
So, can we consider anti-aging facial cream for our cells?
Whereas facial wrinkles are caused by the absence of collagen, cellular wrinkles occur due to the lack of a substance known as lamin, which is part of a protein family responsible for giving the cell its strength and stability.
By replacing the lamin lost through the nuclear membrane or envelope of the cell, researchers believe that they will be able to smoothen out the wrinkles that come with aging. According to researchers, modified viruses would be perfect when it comes to delivering this essential protein at a microscopic level directly to the weakened cell membrane.
In fact, there are various gene therapy practices being undertaken in different medical research institutions that are trying to use engineered viruses to deliver new and vibrant genes by infecting the cells. In case the approach works, individuals will have access to normal and healthy cells that will be appropriately expressed.
These sorts of youthful cells will also help to keep at bay a wide range of aging-related cardio-metabolic conditions like heart disease or diabetes.